The massive atrocities and displacement caused by the rise of the Islamic State of Iraq and Syria (ISIS) is, in no way, different from the mass killings of 1990s in Africa, the Middle East and the Balkans. The lessons of the last decade of 20th century culminated in the Doctrine of ‘Responsibility to Protect’ (R2P). Yet the case of ISIS and its crimes show the intractability of the human nature and the faltering of global institutions — responsible for safeguarding the peace in the world. The persistence of the history of violence is evident that it is mere the change of location; rather than the change of law or evolution of global institutions, which matters and is a common reality. Against this backdrop, this study seeks to address the question of failure of global justice in the face of war crimes committed by ISIS in the Middle East. It will focus on both political and ethical dimensions of the global justice, and will explore as to why despite the global consensus on the Doctrine of R2P, the global community failed to address the causes, which led to the rise of IS and its atrocities lately. In addition, it assesses the political and ethical challenges, which the rise of ISIS brought forth for the implementation of R2P.